Ailments OF USE: The information in this database is intended to health supplement, not substitute for, the skills and judgment of Health care specialists. The knowledge will not be meant to address all possible utilizes, directions, precautions, drug interactions or adverse effects, nor need to or not it's construed to indicate that utilization of a selected drug is safe, suitable or efficient for you personally or anybody else.
Administration of codeine may be accompanied by histamine release and should be made use of with warning in atopic children.
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Promethazine with Codeine Oral Remedy has promethazine, a phenothiazine. Phenothiazines are associated with dystonic reactions, particularly in pediatric patients that have an acute sickness involved with dehydration.
Sedating medications might bring about confusion and more than-sedation inside the elderly; elderly sufferers typically need to be started out on reduced doses of promethazine with codeine syrup and observed closely.
The risk for critical breathing issues is better when You begin this medication, or if you take the wrong dose or choose more of this medication than prescribed. Taking this medication with alcohol or other medications that may cause drowsiness or respiration troubles may well bring about pretty serious Unwanted effects, which include Demise. Also, other drugs can affect the elimination of this item from your body, which may influence how it works.
Promethazine and codeine use is contraindicated in pediatric individuals younger than six yrs. Concomitant usage of promethazine products with other respiratory depressants has an Affiliation with respiratory despair, and from time to time Demise, in pediatric sufferers. Postmarketing situations of respiratory melancholy, together with fatalities, are already claimed with an array of fat-dependent promethazine doses in pediatric individuals more youthful than 2 decades.
Promethazine and codeine need to be made use of throughout pregnancy provided that the potential benefit justifies the probable hazard into the fetus.
Promethazine is metabolized via the liver to several different compounds; the sulfoxides of promethazine and N-demethylpromethazine would be the predominant metabolites appearing during the urine.
Making use of this drugs with any of the next medicines might induce a heightened danger of sure side effects, but working with the two drugs would be the greatest treatment in your case. If each medicines are prescribed together, your health practitioner could alter the dose or how often you use a person or both of those on the medicines.
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Individuals needs to be cautioned to prevent prolonged Solar publicity and report any involuntary muscle movement.
Warning For all individuals taking this drugs: This medication has an opioid drug in it. Opioid medicines can put you in danger for habit, abuse, and misuse. Misuse or abuse of Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) can cause overdose and Loss of life. When you have questions, communicate with your health care provider. This medication has an opioid drug in it. Serious Unwanted side effects have transpired when opioid medications had been used with benzodiazepines or other prescription drugs that may cause you to drowsy or slow your steps. This contains gradual or troubled respiration and Dying. Benzodiazepines incorporate medication like alprazolam, diazepam, and lorazepam. Benzodiazepines may very well be utilised to treat many medical problems like nervousness, hassle sleeping, or seizures. In case you have questions, converse with your physician. Quite a few medication interact with Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) and might elevate the chance of Uncomfortable side effects like deadly respiration challenges. Talk with your medical professional and pharmacist to make sure it really is Harmless to make use of Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) with your entire medicine. Avoid alcohol or other medications and purely natural products that gradual your steps.
Ensure you know how to get this products and what get more info other medication you must stay clear of taking with it. See also Drug Interactions segment. Get clinical assistance immediately if any of those quite really serious Unwanted side effects take place: sluggish/shallow respiration, abnormal lightheadedness, critical drowsiness/dizziness, issue waking up.